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The Nordstrom Family is Paving the Way for Protein Design

Bruce and Jennie Nordstrom received the 2024 Brotman Award for their leadership in supporting the Institute for Protein Design.

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At the UW Medicine Institute for Protein Design (IPD), scientists are creating new proteins to solve a wide range of challenges in medicine, technology and sustainability.

Thanks to a unique collaboration — the visionary leadership of director David Baker, PhD, and the transformative support of Bruce and Jennie Nordstrom — the IPD’s discoveries are on a fast track to worldwide impact. Now, the Nordstroms’ generous support of the IPD is being honored with a 2024 Brotman Leadership Award.

The Brotman Leadership Award recognizes those whose visionary philanthropic leadership significantly impacts UW Medicine’s ability to carry out its mission of improving public health.

“Dr. Baker and his colleagues are the world’s experts in protein design, and we wanted to give them the flexibility to follow their inspiration,” says Bruce Nordstrom.

Founded in 2012, the IPD is a global leader in science with a dual commitment to generating knowledge and achieving impact through protein design. They are redefining what is possible in protein science by unlocking a new era of medical treatments and innovative materials, from next-generation vaccines to technologies that improve drug delivery.

"I am grateful to Bruce and Jeannie Nordstrom for their ongoing support of the Institute for Protein Design. Their early philanthropic gifts helped launch the IPD. They funded early-stage research with generous gifts with flexibility to drive high-risk, high-reward achievements. And they inspired other philanthropists to join them in advancing our research to create new proteins that solve the challenges our world faces today."

- David Baker, PhD, Director, UW Medicine Institute for Protein Design

The Nordstroms believed so strongly in the potential of Baker’s vision that they made leading foundational gifts to advance the institute’s research. Their support gives Baker and his team the flexibility to pursue high-risk, high-reward projects not typically funded by traditional funding sources like grants.

“I am grateful to Bruce and Jeannie Nordstrom for their ongoing support of the Institute for Protein Design,” says Baker. “Their early philanthropic gifts helped launch the IPD. They funded early-stage research with generous gifts with flexibility to drive high-risk, high-reward achievements. And they inspired other philanthropists to join them in advancing our research to create new proteins that solve the challenges our world faces today.”

This flexibility enabled the IPD, in partnership with multiple funders including the National Institutes of Health, the Bill & Melinda Gates Foundation and TED Audacious Project donors, to pivot its research during the pandemic and develop a novel COVID-19 vaccine. This was the first fully approved medicine ever created using computational protein design.

IPD researchers are working to design a pandemic-free future >> Read more

The IPD has also created groundbreaking AI tools for protein science and made them freely available to researchers around the world. These technologies are making protein design more accessible by empowering scientists to generate completely new molecules, including new medicines for dozens of diseases.

The IPD’s innovative use of AI for protein modeling was recognized as the most significant breakthrough in all domains of science in 2021 by the leading research journal Science.

In addition, the IPD is increasing the impact of its discoveries through the formation of new biotechnology companies. Their Translational Investigator Program has become a launchpad for scientific entrepreneurs looking to turn their ideas into real-world results. Trainees receive support and guidance to launch new companies. To date, the program has created 10 new companies in Seattle which together, have raised over $1 billion in venture financing.

“I am honored that Bruce and Jeannie have been IPD’s trusted friends and provided inspiration as we have evolved into a global scientific leader, where the power of our discoveries transforms lives through new therapies and technologies,” says Baker.

“We are thrilled by the progress that Dr. Baker and the team of more than 200 people have achieved at the IPD over 10 years,” says Jeannie Nordstrom.

“We are proud of the IPD’s impact through new vaccines for COVID-19 and RSV, innovative new approaches for cancer treatments and the overarching advances they’ve accelerated in science toward a healthier world.”

By Patsy Cadwell

Cross-Campus Impact

Bruce & Jeannie’s dedication to UW is felt across campus. The Nordstroms have generously supported the UW Department of Athletic programs and scholarships. Bruce has given generously of his time as an executive-in-residence of the Bruce Foster School of Business. The family created the Bruce Nordstrom Endowed Scholarship in 2013, launching support for high-achieving students to overcome financial roadblocks. Whether at Husky football and basketball games, in Foster School lectures or meeting young Nordstrom scholars, Bruce & Jeannie’s joy, dedication and impact at UW is immeasurable.

 


Watch this video to learn about the Institute for Protein Design’s new platform
that uses artificial intelligence to make protein design accessible to anyone.