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Together in Hope

How donor-supported research and care at UW Medicine is changing lives for patients with Alzheimer's disease and dementia.

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UW Medicine is at the forefront of research, education and care for Alzheimer’s disease and other dementias. From becoming one of the first hospitals in the country to administer a groundbreaking new drug therapy to building a hub for community and resilience for people with dementia and their families, we’re redefining what it means to live — and thrive — with memory loss. If you’re looking for compassionate, whole-person care backed by the most advanced research, you’ve come to the right place.

Alzheimer's Disease
Research Center

Dr. Grabowski and colleagues examining research materials through microscopes.

The UW Alzheimer’s Disease Research Center is part of a nationwide network of Alzheimer’s disease research resource centers funded through the NIH’s National Institute on Aging. The ADRC has been committed to helping advance Alzheimer’s research for over 30 years.

Dr. Thomas Grabowski, director of the ADRC (pictured above), leads a team of providers who diagnose, treat and support patients living with memory loss or dementia.

“Donor support expands the scope and possibilities of ADRC research. Because of this generous support, ADRC researchers, especially new investigators, have been able to pursue bold new ideas. Recently, donor funds have supported blood biomarker technology, improved brain imaging protocols and studies of risk genes.”

- Thomas Grabowski

A researcher at the Alzheimer's Disease Research Center (ADRC) holds up a slide of a brain cross-section.

The ADRC focuses on a precision medicine approach to Alzheimer’s disease. Scientists conduct research on genetic risk; develop neuroimaging markers and biomarkers for earlier detection; and seek new therapies that can be tailored to address the underlying molecular causes of an individual person’s disease. Through basic science and clinical studies, they work to find therapeutic strategies that improve the care, functioning and quality of life for patients and caregivers.

"It has been incredible to watch REC trainees advance the work of the ADRC and to watch junior researchers of diverse backgrounds, who received mentoring in the REC, rise through the ranks to become leaders within the ADRC."

- Thomas Grabowski

The ADRC’s Research Education Component is focused on developing the next generation of Alzheimer’s researchers; bringing established researchers from other fields into the Alzheimer’s research community; and giving trainees and investigators from outside institutions access to UW Medicine’s dynamic research and scientific environment. Through programs for trainees, junior investigators and investigators from other fields, our faculty provide Alzheimer’s-focused mentorship, training and access to the data and resources available through the ADRC.

Dr. Grabowski speaking to colleagues at the Alzheimer's Disease Research Center (ADRC).

Memory and Brain
Wellness Center

Andrea Gilbert receiving a lecanemab infusion.

In December 2023, UW Medicine’s Memory and Brain Wellness Center became one of the first West Coast hospitals to give a patient lecanemab — the first FDA-approved drug shown to reduce cognitive decline in people with early Alzheimer’s disease. UW Medicine was selected in part because of its expertise in running large clinical trials and its outstanding reputation as a hub for leading-edge research and care.

"I think the future is looking like a lot more people are going to have Alzheimer’s, so the research going on at the UW is invaluable. I can’t say enough about how lucky and pleased I am to be in this program."

- Andrea Gilbert, who is currently receiving lecanemab at the Memory and Brain Wellness Center

 

Andrea Gilbert

The Memory and Brain Wellness Center (MBWC) envisions a world in which people live well with memory loss and can rely upon the best care within a community of support. The Center’s mission is to promote the well-being of persons living with memory loss and their families by providing exceptional care, advancing scientific understanding and building dementia-friendly communities.

A clinician works with a patient at the Memory and Brain Wellness Center (MBWC).

Located at Harborview Medical Center, the clinical team is focused on providing early and accurate diagnosis of Alzheimer’s disease. Above, a patient is undergoing a cognitive test to help physicians assess a patient’s memory and thinking skills. This information, along with additional tests such as brain scans, informs the basis of a new diagnosis and treatment plan.

A family conference at the Memory and Brain Wellness Center (MBWC).

Providers in the MBWC clinic specialize in evaluating patients whose symptoms may arise from Alzheimer’s disease, frontotemporal degeneration, vascular brain injury, Lewy body dementia or other conditions. After the initial consultation and evaluation, one of the key steps is providing education about the diagnosis and treatment plan, which sometimes happens in a family conference, like the one seen above. Patients and families at the memory clinic are assigned to a primary provider who is the best fit for their situation; they may also meet with social work, neuropsychology or other specialists for a well-rounded approach. The MBWC team helps patients discover ways to use their strengths to promote brain health and overall well-being.

"Early and accurate diagnosis is only the first step in our relationship with our patients who are living with memory loss. We work with them to tailor their treatment to their specific issues as well as to help them make the most of their preserved abilities. One of our goals is to combine leading-edge medications with innovative, strength-based nonmedical interventions and a model dementia-friendly community of support through our unique community center, the Memory Hub."

- Thomas Grabowski

Hikers participating in Shared Outdoor Adventures for Resilience (SOAR), a hiking program for people living with early-onset Alzheimer's.
Photo credit: Nicholas Swatz

The MBWC leads many programs and events for people with Alzheimer’s disease and their families, including Shared Outdoor Adventures for Resilience (SOAR), a hiking program for people living with early-onset Alzheimer’s. The MBWC emphasizes a strengths-based approach, which is a key part of this program, as people diagnosed before age 65 often still have the physical ability for activities like hiking and the need for social engagement and community.

Another focus of the MBWC is educating providers across Washington state on memory loss and dementia. Project ECHO Dementia (Extension for Community Healthcare Outcomes) is a learning model in which front-line care providers from around the state meet in a virtual conference room with an interdisciplinary panel of experts in memory loss and dementia. This innovative, accessible format provides case-based learning where everyone at the table is both a teacher and a learner.

"This project is a wonderful opportunity for clinicians to consult and receive useful information and support in our work with caregivers of patients who have cognitive impairment."

- A provider and ECHO program participant

Clinicians participating in Project ECHO Dementia (Extension for Community Healthcare Outcomes), a learning model in which front-line care providers from around the state meet in a virtual conference room with an interdisciplinary panel of experts in memory loss and dementia.

The Memory Hub

Exterior of the Memory Hub.

The Memory Hub had its grand opening in 2022, established with the help of a generous founding gift from the Richard and Maude Ferry Foundation. The Memory Hub is located on First Hill in Seattle, near Harborview Medical Center and the Frye Art Museum. The goal: to promote the well-being of people living with memory loss and their families and to build dementia-friendly communities. It’s a welcoming, active, inclusive center where many programs are hosted for the entire community.

“Community can be the difference between feelings of despair and feelings of hope — the feeling that you can get through this. By creating the Memory Hub, we are ensuring that people with dementia are woven into the fabric of community life, rather than sidelined and forgotten.”

- Marigrace Becker, director of the Memory Hub

 

Marigrace Becker, director of the Memory Hub, hugs a visitor.

A Memory Hub visitor admires a yellow rose.

A signature highlight of the Memory Hub is Maude’s Garden, a spot for drop-in exploration, socializing and nature-based activities. Therapeutic landscape design taps into the health benefits of nature and allows nature to be built into visitors’ experience. Maude’s Garden is the site of many events and workshops around the year.

“I appreciated being able to use our hands to create something that ended up beautiful. It’s nice to be able to make memories with my brother,” said a participant in the garden discovery program.

An exhibit called “Frame of Mind” hanging in the atrium of the Memory Hub, which features artwork created by people with memory loss and dementia.

In the Memory Hub’s atrium, an exhibit called “Frame of Mind” features artwork created by people with memory loss and dementia. A reminder of the many gifts, strengths and unique perspectives that people with memory loss offer, the exhibit is open to the public four days each week and can be viewed online.

“So many people with memory loss and cognitive challenges, like myself, are often lost in the shadows of their families and community. Art has been a catalyst in my life!”

- artist Kimberley Rettig

Visitors participating in a karaoke and tai chi program at the Memory Hub.

There are many programs offered at the Memory Hub — including support groups, educational workshops, book and music groups — that are intended for caregivers or people living with memory loss, and some for both at once.

In 2024, the Memory Hub partnered with Kin On to begin offering very popular Chinese-language brain health programs, especially a Tai Chi and Karaoke program shown above, which promotes connection with others through movement and song.

You Can Help Prevent Memory Loss

Your generosity can help advance the groundbreaking research, care and education needed to prevent or delay dementia.